The diagram depicts a typical CMA method. Initially, the reference DNA (in red) is placed on a microslide and the test DNA (in green) from the patient is extracted, purified, denatured (strand separation), and then hybridized to the complimentary DNA probes on the slide. The slide containing the differentially-labeled DNA (patient and reference) produces signal outputs that are then scanned and analyzed by a computer-based analyzer. Normal pieces of DNA hybridized equally will produce a yellow signal, whereas extra pieces of DNA (duplication) will yield a green signal and missing pieces of DNA (deletions) produce a red signal.