Systemic lupus erythematosus (SLE) is an autoimmune disorder. SLE is a result of many autoantibodies, in particular antinuclear antibodies (ANA). It is characterized by multisystem microvascular inflammation. This systemic disease suppresses the immune system, impairing the body’s ability to fight infection. SLE is associated with diverse skin, kidney, hematological, and musculoskeletal abnormalities. SLE can present major challenges because of accrued organ damage, coagulation defects, and it can be fatal depending on organ involvement.
