Example Of A Naturally Occurring Antibody

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The page below is a sample from the LabCE course Antibody Detection and Identification. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Example Of A Naturally Occurring Antibody

In this example, anti-M can be identified as the possible antibody by looking at the patterns of reactivity. Reactions are only occurring at immediate spin, so this would not be considered a clinically significant antibody.
Clinically significant antibodies are usually IgG and react at 37°C and at the AHG phase.
Rh-HrKellDuffyKiddLewisMNSsLutheran
VialDonorDCcEefVCwKkKpaKpbJsaJsbFyaFybJkaJkbLeaLebMNSsLuaLubISAHGCC
IR1R1++00+000++0+0++++00++00+0+2+02+
IIR2R2+0++00000+0+0++0+++0++++0+2+02+
Rh-HrKellDuffyKiddLewisMNSsPLutheran
Donor Cell NumberDCcEeCwKkKpaKpbJsaJsbFyaFybJkaJkbLeaLebMNSsP1LuaLubISAHGCC
1++00+00+0+0++0+++0+++++0+1+02+
2++00++++0+0+++0+0+0++++0+002+
3+0++000+0+0+0+0+0++00++0+1+02+
4+0+0+00+0+0+00+00++++0+0+1+02+
50++0+00+0+0++++++00+0+00+002+
600+++0++0+0+0+++0+++++00+1+02+
700+0+00+0+0++00++0+00++0+1+02+
800+0+00+0+0+++0+0+++++00+1+02+
900+0+00+0+0++++00+0++0+0+002+
10+0+0+0++0+0+0+0+0+0++0+0+002+
AC 002+
IS = Immediate Spin; AHG = Antihuman Globulin Phase; CC = Check Cells; NT = Not Tested; AC = Auto Control