Hemoglobin Electrophoresis Patterns in Beta Thalassemia

How to Subscribe
MLS & MLT Comprehensive CE Package
Includes 176 CE courses, most popular
$109Add to cart
Pick Your Courses
Up to 8 CE hours
$55Add to cart
Individual course$25Add to cart
Need multiple seats for your university or lab? Get a quote
The page below is a sample from the LabCE course Beta Thalassemia. Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

Learn more about Beta Thalassemia (online CE course)
Hemoglobin Electrophoresis Patterns in Beta Thalassemia

The following list corresponds to this image of alkaline hemoglobin electrophoresis.

Lanes 1 and 2: normal patient specimen
Hb A is over 98%, with a small amount of Hb A2 visible.

Lanes 3 and 4: Beta thalassemia minor
Hb A is decreased to 94%, Hb A2 is increased at 5%, and Hb F is 1%

Lanes 5 and 6: Delta-beta thalassemia major
No Hb A or A2 is present, Hb F is 100%

Lanes 7 & 8: Delta-beta thalassemia intermedia
Hb A is 8.5%, Hb A2 is 3.5% and Hb F is 88%

Lane 9: AF control
Lane 10: ASC control

(Remember, AF and ASC are labels and do not indicate the order of migration.)