Ideally, for a tumor marker to be considered as a screening tool, it should be consistently elevated at early stages of disease so that the diagnostic sensitivity is near 100%, and elevated only when the cancer of interest is present so that the diagnostic specificity is near 100%.

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The page below is a sample from the LabCE course Tumor Markers (retired 12/7/2020). Access the complete course and earn ASCLS P.A.C.E.-approved continuing education credits by subscribing online.

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Ideally, for a tumor marker to be considered as a screening tool, it should be consistently elevated at early stages of disease so that the diagnostic sensitivity is near 100%, and elevated only when the cancer of interest is present so that the diagnostic specificity is near 100%.

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